This is a good close matchup that will boil down to shape preference, ambidextrous or ergonomic.

Both mice have great shapes that suit multiple grip style and are a dream to hold and both mice have flawless sensors.

The S2 has a few advantages over the EC2, it has a cable that drags less, it's lighter and it has more responsive and lighter buttons. Though none of these advantages outweigh shape preference.

It's hard to call, you can't go wrong with either but you have to determine whether you'd like an ambi or ergo shape.

Side-by-Side Comparison

Mouse nameZowie EC2Zowie S2
PictureZowie EC2 - Check Priceread review
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Zowieread review
Check Price on Addice
Length12cm12.2 cm
Width6.1cm5.9 cm
Height4cm3.8 cm
Weight93g82 g
Buttons2 Primary Buttons
1 Middle Scroll Button
1 DPI Button
2 Side buttons
2 Primary Buttons
1 Middle Scroll Button
1 DPI Button
2 Side buttons
SensorPixart PMW3360Pixart PMW3360
ShapeErgonomicAmbidextrous
Cable/WirelessSoft rubber cableSoft rubber cable
Battery LifeN/AN/A
SoftwareNo software:
DPI settings are preprogrammed
Step 1: 400 DPI
Step 2: 800 DPI
Step 3: 1600 DPI
Step 4: 3200 DPI
No software:
DPI settings are preprogrammed
Step 1: 400 DPI
Step 2: 800 DPI
Step 3: 1600 DPI
Step 4: 3200 DPI
WarrantyUnknown lengthUnknown length
ProsComfortable super popular shape
Flexible rubber cord
Flawless sensor
Safe shape, well balanced
Improved lighter buttons
Flexible rubber cable
Flawless sensor
Plug and play
Good light weight at 82 grams
ConsLoud scroll wheel
Issues with accidental clicks
Glossy coating picks up dirt
Noisy scroll wheel

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